In Alzheimer’s disease, damage to the brain likely starts a decade or more before memory and other cognitive problems appear. Learn about the toxic changes occurring in the Alzheimer’s brain.

How is the brain affected by Alzheimer’s disease? Read how genetics, environment, and lifestyle play a role in developing early- or late-onset Alzheimer’s.

What are risk factors for Alzheimer’s disease? Learn about genetic and other risks for early- and late-onset Alzheimer’s and steps you can take to stay healthy.

Read about the genetics of Alzheimer’s disease and related research. A genetic mutation can cause early-onset Alzheimer’s. Genetic variants influence disease risk.

Many, but not all, people with Down syndrome develop Alzheimer’s disease when they get older. Learn about the connection between the two and how to participate in research studies exploring this relationship.